Scientist II, QSP/QST Consulting Services

Accountabilities

• ScientificModelingandSimulation:Design,develop,test,andmaintaincomputationalsubmodelsrepresentingcellular,molecular,andbiochemicalprocesses.ApplyQSPandQSTmethodologiestoinvestigatedrugpharmacodynamics,mechanismsofaction,andpotentialtoxicologicaleffects.

• DataIntegrationandModelValidation:Translatelaboratoryandexperimentalfindingsintomodelparameters,curateclinicaldatasets,andsupportmodelcalibrationandvalidationtoimprovethereliabilityandscientificrelevanceofsimulationresults.

• ConsultingProjectDelivery:Contributetothesuccessfulexecutionofclientprojectsbycompletingassignedtechnicalactivities,coordinatingwithinternalandexternalcollaborators,anddeliveringhigh-qualityscientificoutputswithinagreedtimelinesandprojectbudgets.

• SoftwareDevelopmentandTechnicalImplementation:Applyprogrammingandmodelingtools,includingMATLAB,THALES,Julia,SimBiology,Monolix,andotherrelevanttechnologies,todevelopscripts,maintainmodelcomponents,andsupporttechnicalconsultingdeliverables.

• ResearchandDevelopment:ParticipateinR&Dinitiatives,maintainproduction-readyandlicense-readymodelversions,andcontributetotheongoingdevelopmentofQSTmodels,includingresearchrelatedtodrug-inducedliverinjury.

• ScientificCommunicationandPublications:Prepareandreviewtechnicalreports,presentations,figures,andscientificdocumentation.Contributetojointmanuscripts,journalsubmissions,andcorrespondencewitheditorsandpeerreviewerswhilerespondingconstructivelytoscientificfeedback.

• ProjectCoordinationandPlanning:Organizeprojectactivities,schedulemeetings,developplansforcompletingassignedtasks,andmanageworkloadinlinewithcontractualcommitmentsandallocatedresources.

• EmergingTechnologyAdoption:LearnandapplyagenticAIsolutionstosupporttechnicalwork,improveresearchefficiency,andenhancemodelingandsimulationworkflows.

• KnowledgeSharingandCollaboration:ShareexpertiseinQSP/QSTmethodologiesandmodelingtools,supportcolleagues'development,andcontributetoacollaborativescientificenvironment.Taketheleadonconsultingprojectswhentechnicalproficiency,projectmanagementexperience,andprojectavailabilitypermit.

Requirements

• Education:Amaster'sdegreeinpharmaceuticalsciences,biomedicalengineering,orarelatedscientificdisciplineisrequired.APhDinpharmaceuticalsciences,biomedicalengineering,orarelatedfieldispreferred.

• RelevantExperience:AtleasttwoyearsofexperienceinQSP/QSTmodeling,ordemonstratedequivalenttechnicalcapabilities.

• ScientificKnowledge:Strongfoundationinmathematics,dynamicsystems,anddrugdevelopment,withageneralunderstandingofrelevanttherapeuticareas,clinicalendpoints,cellularandmolecularbiology,andbiochemistry.

• ModelingandProgrammingSkills:Experiencewithoneormoreofthefollowingtoolsandtechnologies:MATLAB,THALES,Julia,SimBiology,Monolix,GastroPlus™,orC++.

• PharmacokineticModeling:Experiencewithphysiologicallybasedpharmacokinetic(PBPK),pharmacokinetic(PK),populationpharmacokinetic(popPK),orpharmacokinetic/pharmacodynamic(PK/PD)modelingisdesirable.

• AIandComputationalTools:BasicfamiliaritywithlargelanguagemodelsandagenticAI,alongwithaninterestinapplyingemergingtechnologiestoscientificresearchandtechnicalworkflows.

• AnalyticalandProblem-SolvingSkills:Abilitytointerpretcomplexscientificdata,developquantitativemodels,andapplymodelingandsimulationtechniquestoaddressdrugdevelopmentchallenges.

• CommunicationSkills:Strongwrittenandverbalcommunicationabilities,includingthecapacitytoprepareclearscientificreports,delivereffectivepresentations,andcollaboratewithcolleaguesandclients.

• OrganizationandAccountability:Strongtimemanagement,organizational,andmultitaskingskills,withtheabilitytomanagecompetingprioritiesanddeliveraccurateworkwithminimalsupervision.

• TeamworkandProfessionalism:Aproactive,self-motivatedapproach,apositiveattitude,andtheabilitytoworkeffectivelyinmultidisciplinaryteams.

• AdditionalRequirements:Willingnesstotraveloccasionallyforscientificconferences,meetings,andtraining.

Benefits

• CompetitiveSalary:Annualsalaryrangeof$110,000–$130,000,dependingonqualificationsandexperience.

• RemoteWork:FullyremotepositionofferingflexibilitytoworkfromhomewithintheUnitedStates.

• FlexibleScheduling:Flexibleworkarrangementsdesignedtosupportproductivityandwork-lifebalance.

• AnnualBonus:Eligibilityforanannualbonus,subjecttoapplicableprogramterms.

• HealthcareCoverage:Accesstoaffordablehealthinsuranceoptions.

• PaidTimeOff:Generousvacationpolicytosupportrestandpersonalwell-being.

• ProfessionalDevelopment:Opportunitiestoexpandexpertiseincomputationalpharmacology,toxicologymodeling,drugdevelopment,andscientificconsulting.

• ResearchandInnovation:Exposuretoadvancedscientificsoftware,AI-enabledsolutions,multidisciplinaryresearchinitiatives,andcollaborativepharmaceuticaldevelopmentprojects.

• ScientificCareerGrowth:Opportunitiestocontributetopublications,developtechnicalleadershipskills,andprogresstowardleadingconsultingengagements.

• SupportiveWorkEnvironment:Acollaborativeculturethatvaluesscientificexcellence,employeewell-being,andcontinuouslearning.