Sr. Program Strategy and Operations Director

<h3>Accountabilities:</h3><li>Act as a strategic thought partner to the Asset Entrepreneur, anticipating key program inflection points and evaluating scenarios to determine when to accelerate, pivot, or pause development activities.</li><li>Own end-to-end program execution, operating as the operational lead for a single-asset biotech program and ensuring priorities, decisions, resources, and dependencies remain aligned.</li><li>Coordinate closely across clinical, translational, regulatory, CMC, commercial, and other functional teams to maintain momentum and resolve obstacles.</li><li>Identify and address execution gaps proactively, including coordinating internal stakeholders, mobilizing CROs and external partners, and creating practical solutions when challenges arise.</li><li>Translate complex scientific, clinical, regulatory, and operational information into concise analyses, recommendations, presentations, and executive-level communications.</li><li>Prepare clear, data-driven materials for C-suite leadership, Board discussions, investor engagements, and business development activities.</li><li>Maintain disciplined program documentation, including key decisions, assumptions, benchmarks, dashboards, trackers, and action plans.</li><li>Manage external vendors, advisors, CROs, and strategic partners while building relationships with leading experts within the relevant disease area.</li><li>Support the development of scientific narratives around novel molecules and emerging biology, helping communicate their potential to patients, clinicians, investors, and other stakeholders.</li><li>Contribute to company-wide operating knowledge by documenting benchmarks, lessons learned, best practices, and scalable approaches for future programs.</li><li>Support the evolution of organizational culture, operating models, and processes as the organization expands across multiple diseases, mechanisms, and future commercial opportunities.</li><li>Travel approximately monthly to meet with internal teams and key external stakeholders.</li><h2>Requirements:</h2><li>Significant experience in biotech or pharmaceutical program management, portfolio or asset strategy, management consulting, business operations, or a comparable strategic role.</li><li>Demonstrated ability to connect strategic thinking with hands-on execution in complex, cross-functional environments.</li><li>Strong understanding of drug development and the ability to work effectively across clinical, translational, regulatory, CMC, and commercial disciplines.</li><li>Proven ability to synthesize large volumes of complex information into clear, actionable insights and compelling executive-level recommendations.</li><li>Exceptional written and verbal communication skills, including the ability to produce concise, data-driven presentations, slides, and executive memos.</li><li>Strong analytical and problem-solving capabilities, with the judgment to evaluate risks, trade-offs, scenarios, and program inflection points.</li><li>Demonstrated fluency with AI tools and the ability to incorporate AI into workflows as a practical multiplier of human judgment, creativity, and productivity.</li><li>Hands-on, entrepreneurial mindset with a willingness to personally address gaps and execute beyond traditional role boundaries when necessary.</li><li>Ability to thrive in ambiguity, move comfortably between long-term strategy and tactical execution, and maintain momentum in a rapidly evolving environment.</li><li>Strong emotional intelligence, humility, integrity, and collaborative leadership style.</li><li>High intellectual curiosity, analytical rigor, optimism, and the ability to motivate and align diverse stakeholders.</li><li>Willingness to travel approximately once per month for team and external stakeholder engagements.</li><li>A growth-oriented mindset and demonstrated trajectory are valued alongside traditional credentials.</li><h2>Benefits:</h2><li>Annual salary range of<strong>$275,000–$300,000</strong>.</li><li>Fully remote position within the United States.</li><li>Medical, dental, and vision coverage at<strong>90%</strong>, beginning on the first day.</li><li>
<strong>401(k) plan with company match</strong>.</li><li>Flexible paid time off.</li><li>Company-wide weeklong recharge break.</li><li>Adoption assistance.</li><li>Opportunity to work at the intersection of AI, drug discovery, science, strategy, and operations.</li><li>High-impact position with direct visibility into strategic decisions, asset development, investor engagement, and company building.</li><li>Opportunity to work closely with senior scientific, clinical, commercial, and executive stakeholders.</li><li>Significant autonomy and ownership within a fast-growing biotech environment.</li><li>Opportunity to help establish operating practices and institutional knowledge that will shape future development programs.</li>